The active ingredient hyoscine butylbromide, in Buscopan® Cramps, is derived from natural hyoscine extracted from the leaves of an Australian native shrub, known as the corkwood tree or Duboisia. Boehringer Ingelheim, maker of Buscopan® Cramps, is the world's leading grower of Duboisia, delivering by far the biggest part of the global requirement for the ingredient. Using sophisticated and environmentally-friendly farming methods, farmers in Australia grow and harvest the small shrubs. The dried leaves are used to create the high quality pharmaceutical product.